Product Packing: 60 ML
Product Composition: Mefenemic Acid 100 mg + Paracetamol 250 mg
Product Price: MRP :
MEFIMIC-P DS is
an oral suspension containing Mefenamic Acid 100 mg and Paracetamol 250 mg as
the declared combination strength. Mefenamic Acid is a non-steroidal
anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory actions,
while Paracetamol is an analgesic and antipyretic. The combination may be used
for short-term symptomatic relief of pain and fever where approved and
clinically appropriate.
Mefenamic Acid reduces prostaglandin synthesis
through cyclo-oxygenase inhibition, while Paracetamol acts mainly within the
central nervous system to reduce pain perception and elevated body temperature.
Dosing must follow the exact approved concentration per measured volume,
age/weight requirements and professional advice.
Each labelled dose contains:
Β·
Mefenamic Acid - 100 mg
Β·
Paracetamol - 250 mg
Β·
Suspension base / excipients - q.s. Exact
strength per ml or per measured dose must be verified from the approved product
label.
Dosage form: Oral Suspension
Uses of MEFIMIC-P DS
MEFIMIC-P DS may
be used for short-term symptomatic relief of pain and fever where the Mefenamic
Acid + Paracetamol combination is approved and clinically appropriate.
Β·
Helps reduce mild to moderate pain according
to approved prescribing information
Β·
Helps reduce fever through the antipyretic
action of Paracetamol
Β·
Mefenamic Acid contributes analgesic and
anti-inflammatory activity where inflammation is associated with pain
Β·
Liquid suspension allows accurately measured
administration according to the approved dose
How
MEFIMIC-P DS Works
MEFIMIC-P DS combines two complementary pain- and fever-relieving mechanisms:
Mefenamic Acid: An NSAID that inhibits
cyclo-oxygenase enzymes and reduces prostaglandin synthesis, helping relieve
pain and inflammation.
Paracetamol: Acts mainly centrally to reduce pain
perception and lower elevated body temperature.
Clinical response depends on the cause of symptoms, correctly measured
dose, treatment duration and individual patient factors.
The
total daily exposure to Mefenamic Acid, Paracetamol and other NSAID- or
Paracetamol-containing medicines must be considered to avoid duplicate
dosing.
Dosage
and Direction for Use
Use MEFIMIC-P DS exactly according to the approved product
label or healthcare professional's directions. The dose must be based on the
exact concentration per measured volume, age, weight and clinical situation.
Shake
the suspension well before each dose and measure it with a calibrated oral
syringe, cup or other appropriate measuring device.
Do not combine with another NSAID or
Paracetamol/Acetaminophen-containing medicine unless specifically advised by a
healthcare professional.
Possible
Side Effects
Possible
unwanted effects may include:
Β·
Nausea, vomiting, abdominal discomfort, indigestion or diarrhoea
Β·
Headache, dizziness or mild skin reactions
Β·
Mefenamic Acid can cause gastric irritation, ulceration or
gastrointestinal bleeding, particularly in susceptible patients or with
excessive/prolonged use
Β·
Excessive Paracetamol dosing can cause serious liver injury; NSAIDs can
also affect kidney function, fluid balance and cardiovascular risk in
susceptible patients
Persistent or troublesome adverse effects should be discussed with a
healthcare professional.
Precautions
and Contraindications
Before
using MEFIMIC-P
DS, review
age, weight, dehydration status, allergy history, stomach-ulcer/bleeding
history, asthma, kidney or liver disease and all other medicines being taken.
Β·
Avoid in patients with known hypersensitivity to Mefenamic Acid,
Paracetamol, aspirin/other NSAIDs or formulation ingredients according to
approved prescribing information.
Β·
NSAIDs require caution in gastrointestinal ulcer/bleeding risk, kidney
disease, significant dehydration, cardiovascular disease and patients with
NSAID-sensitive asthma.
Β·
Avoid duplicate Paracetamol-containing medicines and avoid using another
NSAID at the same time unless specifically prescribed.
Β·
Mefenamic Acid should generally be used for the shortest appropriate
duration. Significant dehydration can increase NSAID-related kidney risk.
Β·
Use during pregnancy, especially later pregnancy, requires professional
guidance because NSAIDs have important pregnancy-related restrictions.
Β·
Breastfeeding, children, older adults and patients with significant
chronic conditions require individualized professional guidance.
Β·
Drug Interaction Considerations
Β·
Clinically relevant interactions may involve
anticoagulants/antiplatelets, corticosteroids, other NSAIDs, certain
antihypertensives and diuretics, lithium, methotrexate and medicines affecting
kidney function. Prolonged regular Paracetamol use may also interact with
anticoagulant therapy.
Business
Growth Opportunity with MEFIMIC-P DS
MEFIMIC-P DS offers pharmaceutical distributors and healthcare entrepreneurs an
opportunity to add a Mefenamic Acid 100 mg + Paracetamol 250 mg oral
suspension in a 60 ml pack to their pain and fever management portfolio.
Key Business Advantages
Β·
Dual analgesic and antipyretic formulation
Β·
Mefenamic Acid 100 mg + Paracetamol 250 mg
Β·
NSAID + Paracetamol combination
Β·
Convenient 60 ml oral suspension pack
Β·
Suitable addition to pain and fever management portfolios where the
combination is approved and clinically appropriate
PCD
Pharma Franchise Opportunity for MEFIMIC-P DS
Ethics Medinova Private Limited offers PCD Pharma Franchise
opportunities for MEFIMIC-P DS in selected territories across India, subject to availability,
applicable regulations and mutually agreed business terms.
Franchise Support May Include
Β·
Monopoly-based territory opportunities, subject to availability
Β·
Promotional materials and visual aids
Β·
Product information and marketing support
Β·
Reliable supply coordination
Β·
Access to a growing pharmaceutical product portfolio
Β·
Professional partner assistance
Third-Party
Manufacturing Support for Mefenamic Acid + Paracetamol Suspension
Ethics
Medinova also supports eligible businesses exploring third-party
manufacturing of formulations similar to MEFIMIC-P DS under their own
brand, subject to applicable licensing, regulatory and manufacturing
requirements.
Our
third-party manufacturing support may include:
Β·
Customized product and pack requirements, subject to regulatory
feasibility
Β·
Private-label manufacturing opportunities
Β·
Customized packaging and branding support
Β·
Product label and pack configuration assistance
Β·
Manufacturing coordination through suitable licensed facilities
Β·
Support for documentation and applicable regulatory requirements
1. What is MEFIMIC-P DS?
2. What is MEFIMIC-P DS used for?
3. How should MEFIMIC-P
DS be measured?
4. Can MEFIMIC-P DS be given with another pain or fever medicine?
5. What are important Mefenamic Acid
precautions?
6. What should be done after a
suspected overdose?
7. Is a PCD Pharma Franchise available
for MEFIMIC-P DS?
8. Can this formulation be manufactured
under my own brand?
Disclaimer